1st Struchkov Meeting (2007)

Structural methods in chemistry, biology and medicine.

(Workshop in memory of Prof. Yuri Struchkov)

Chicago, Aug 10-13, 2007.


The Workshop will focus on the fields of chemistry and chemical biology that utilize X-ray diffraction and molecular modeling to characterize novel materials and establish structure-property relationships in the worlds of small and large molecules. It will highlight the scientific achievements and research of the colleagues who knew and collaborated with Professor Struchkov and continue to use structural methods in their current work. The Workshop will enable the old friends and colleagues to forge new bonds and discover novel grounds for future interactions, idea exchange, and collaborations.


This is the scientific program of the Workshop.
Presentations will be made either in Russian or in English. Translation will not be provided.

Saturday, August 11, 2007

09:00-09:45 M.Yu.Antipin (Institure of Organoelement Compounds, Moscow, Russia):
Opening remarks. History of the Society
09:45-10:30 V.E.Shklover (Eidgenossische Technische Hochschule, Zurich, Swtzerland):
Photonic materials: fabrication, modeling, and applications
10:30-11:00 Coffee break
11:00-11:45 I.L.Dubchak (Lawrence Berkeley National Laboratory, Berkeley, CA, USA):
Comparative genomics – what is it?
11:45-12:30 A.B.Zolotoy (Astrum therapeutics, Melbourne, Australia):
Charge and charge shielding as the main determinants of drug-induced HERG channel blockade. Approach to reduce potentially lethal effect of HERG channel inhibition
12:30-2:00 Lunch break
2:00-2:45 M.Yu.Antipin (Institure of Organoelement Compounds, Moscow, Russia):
Structural studies at the X-Ray Structural Center INEOS: then and now
2:45-3:30 T.V.Timofeeva (New Mexico Highlands University, Las Vegas, NM, USA):
Compounds for photodynamic therapy: structure and properties
3:30-4:00 Coffee break
4:00-4:45 S.V.Lindeman (Marquette University, Milwaukee, WI, USA):
Crystallographic feedback to chemistry – beyond just pictures
4:45-5:30 O.Ya.Borbulevych (University of Notre Dame, IN, USA):
Cross-reactivity of TCR A6 on haptenated HTLV-1 Tax11-19 peptides presented by HLA-A2
5:30-5:45 I.A.Guzei (University of Wisconsin-Madison, WI, USA):
Announcement and registration for the Bruker-AXS visit on 8/13/07 (see Social events page)
6:00 Departure for the banquet

Sunday August 12, 2007

09:30-9:45 M.Yu.Antipin (Institure of Organoelement Compounds, Moscow, Russia):
Opening remarks
09:45-10:30 S.K.Byram (Bruker-AXS, Madison, WI, USA):
Evolution of hardware and software for single-crystal X-ray diffractometry
10:30-11:15 C.F.Campana (Bruker-AXS, Madison, WI,USA):
New tools for the solution and refinement of problem structures
11:15-11:45 Coffee break
11:45-12:30 S.E.Nefedov (Institute of General and Inorganic Chemistry, Moscow, Russia):
Binuclear transition-metal trimethylacetato complexes as structural analogues of the active site of metalloenzymes
12:30-2:00 Lunch break
2:00-2:45 E.G.Mednikov (University of Wisconsin-Madison, WI, USA):
Pd10 Cluster chemistry
2:45-3:30 E.Skrzypczak-Jankun (Medical University of Ohio, Toledo, OH, USA):
Toward understanding of human lipoxygenases
3:30-4:00 Coffee break
4:00-4:45 I.I.Vorontsov (Northwestern University, Chicago, IL, USA):
Structural genomics at Midwest Center for Structural Genomics
4:45-5:00 M.Yu.Antipin (Institure of Organoelement Compounds, Moscow, Russia):
Closing remarks

Social Events

August 11, 2007, 6 pm – 11 pm
Tour to Bruker AXS facility
August 13, 2007, 7:45 am -6:00 pm.
Optional one-day tour to Bruker facility in Madison, Wisconsin
will be organized by Bruker AXS and University of Wisconsin-Madison (I.A.Guzei).A 14 passenger bus type van will shuttle people to Bruker in Madison, WI.
The tour will start at the Oak Brooks hotel at 7:45 am and participants will be brought back
to the hotel or airport by ~6:00 pm. Lunch will be generously provided by Bruker.
The number of seats is limited and seating is available on the first come, first served basis.
People should indicate their interest in the tour at their earliest convenience.


Organizing Committee

M.Yu.Antipin (Chairman)
+7(495)135 9215
m_antipin at yahoo.com

+1(574)631 2601
oborbulevych at yahoo.com

+1(510)495 2419
ildubchak at lbl.gov

+1(608)263 4694
iguzei at chem.wisc.edu

+1(505)454 3362
t_timofeeva at yahoo.com

+1(858)638 3716
alex.yanovsky at pfizer.com